Jiří Jiráček Group at IOCB Prague is interested in all aspects of insulin and insulin-like growth factors 1 and 2 (IGF-1/2) physiology. We synthesize analogs and mimetics of insulin and IGFs to study their biological effects and to develop new drugs for treatment of hormone-related disorders. We are looking for talented and motivated peptide chemist to join our team.

The successful candidate for this position will be developing new chemical approaches for total chemical synthesis of small proteins with a special focus on insulin-like family of hormones.

Required knowledge and skills:

• PhD degree in organic chemistry obtained no more than 5 years ago
• Good track record of previous scientific publications and achievements
• Fluency in spoken and written English
• Passion for basic research and synthetic chemistry
• Previous experience with solid-phase peptide synthesis is an advantage, but not a prerequisite
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We offer:

• Stable background of an internationally recognized scientific institution
• Opportunity to work in a progressive multidisciplinary scientific team of medicinal chemists, virologists, immunologists, computational chemists, biologists, and biochemists
• Access to state-of-the-art instrumentation
• Training and opportunities for specialized courses
• Competitive financial remuneration
• 5 weeks of vacation + 4 days of personal leave
• Financial support for parents with children under 4 years of age returning to work after maternity/parental leave
• Employee benefits (meal subsidy, on-site catering facility at IOCB, contribution to supplementary pension insurance/leisure activities, Multisport card, discounted language courses)

Additional information:

• Full-time employment contract initially for 1 year with the possibility of extension
• Start date: immediately

How to apply:

• Please send your CV and a short motivation letter with two references no later than by 15 December 2024 to Dr. Jiří Jiráček at jiri.jiracek@uochb.cas.cz.

If you do not hear from us within 3 weeks, we have decided to proceed with another candidate. Thank you for your understanding.

IOCB Prague is a leading internationally recognized scientific institution whose primary mission is the pursuit of basic research in chemical biology and medicinal chemistry, organic and materials chemistry, chemistry of natural substances, biochemistry and molecular biology, physical chemistry, theoretical chemistry, and analytical chemistry. An integral part of the IOCB Prague’s mission is the implementation of the results of basic research in practice. Emphasis on interdisciplinary research gives rise to a wide range of applications in medicine, pharmacy, and other fields.