진학프로석·박사 채용 접수 플랫폼

The job offer refers to the position in the Opus LAP project (National Science Center) titled “Engineering Biocompatible and Bioactive Stents for Improved Endothelial Integration in Cardiovascular Applications” (Contract number: 2024/55/I/ST5/02185) under the supervision of principal of the project - dr Jagoda Litowczenko-Cybulska.

This project aims to develop next-generation bioactive, slowly degradable stents for applications in cardiovascular disease. By combining naturally derived and synthetic polymers, the stents will feature improved mechanical stability, biocompatibility, and the ability to support the growth of a functional endothelial cell layer. A bioactive surface will be incorporated to enhance the interaction between the stent and surrounding tissue, improving long-term performance.

The work will involve advanced material synthesis, characterization, drug release studies, antibacterial assays, and biological evaluation under in vitro, ex vivo, and in vivo conditions using a porcine model. The project will also utilize volumetric bioprinting to deposit functional layers inside the stent lumen, as well as computational simulations and perfusion bioreactor systems to optimize design and performance. The final goal is to deliver a prototype of a 3D-printed or casted bioactive stent with proven tissue compatibility and mechanical stability, paving the way for improved cardiovascular implants.

The Opus LAP project includes international collaboration with the Institute of the Czech Academy of Sciences, providing access to complementary expertise and facilities. 

The postdoctoral scientist will mainly be responsible for managing experiments in design and synthesis of biomaterials, 3D printing and characterization, drug releasing studies, microfluidics as well as cell biology tests.

This project will be carried out at the Center for Advanced Technologies (CAT), Adam Mickiewicz University in Poznań. AMU is one of the leading scientific institutions in Poland, consistently ranked among the top four research universities in the country, and is equipped with state-of-the-art infrastructure. The university achieved the highest ranking—1st place in Poland—in the category of building international research networks. This metric evaluates the durability and diversity of international scientific partnerships resulting in joint publications.

The Center for Advanced Technologies (CAT) brings together experts in chemistry, engineering, and biology to work on innovative projects in the fields of biomaterials, and medical, environmental, and industrial biotechnology. JagodaLab's research focuses on the development of novel biomaterials for 3D bioprinting, stem cell research, and cell differentiation.

JagodaLab is equipped with multiple 3D printers, including Poland’s first volumetric bioprinter, an extrusion-based bioprinter, SLA printers. CAT also houses fully equipped chemical and biological laboratories. The group has strong expertise in the field of biofabrication, including the development of printable materials and their characterization (e.g., rheology, FTIR, UV-Vis, SEM, mechanical testing, NMR), as well as cell culture and biological analysis.