진학프로석·박사 채용 접수 플랫폼

Project: “Exploring the role of non-coding RNAs in 3D chromatin Hubs” – Acronym: 3D-Hubs – Grant Agreement number: FIS-2023-02410 – CUP: J53C24004180001

Contract: Fixed-term contract, full time

Duration: up to 3 years

Location: Genova CHT@Erzelli

Step into a world of endless possibilities, together let’s leave something for the future!

At IIT, we are committed to advancing human-centered Science and Technology to address the most urgent societal challenges of our era. We foster excellence in both fundamental and applied research, spanning fields such as neuroscience and cognition, humanoid technologies and robotics, artificial intelligence, nanotechnology, and material sciences, offering a truly interdisciplinary scientific experience. Our approach integrates cutting-edge tools and technology, empowering researchers to push the limits of knowledge and innovation. With us, your curiosity will know no bounds.

We are dedicated to providing equal employment opportunities and fostering diversity in all its forms, creating an inclusive environment. We value the unique experiences, knowledge, backgrounds, cultures, and perspectives of our people. By embracing diversity, we believe science can achieve its fullest potential.

THE ROLE

You will be working in a multicultural and multi-disciplinary group, where junior and senior scientists collaborate, each with their expertise, to carry out a scientific activity with a shared research goal. 

The “3D Chromatin Conformation and RNA Genomics” Research Unit is coordinated by Dr. Dafne Campigli Di Giammartino and aims at understanding how non-coding elements (DNA/RNA) and their epigenetic/epitranscriptomic modifications regulate 3D genome architecture and gene expression. To address this question, we use cutting-edge chromatin conformation assays (e.g.Hi-C, Hi-ChIP etc) in conjunction with other -omics techniques (e.g. ChIPseq, RNA-seq etc.) and in combination with CRISPR-based genetic and epigenetic engineering tools in mouse stem cells as well as in human tumor stem cells.

Moreover, as a member of the FANTOM6 consortium, bioinformaticians in our lab have the opportunity to attend and actively participate to this international consortium with ample opportunities for collaborations within the IIT and with extramural institutions to implement new workflows and pipelines

As a key member of our research team, you will: 

• Analyzing in-house produced NGS data (ChIP-seq, RNA-seq, Hi-C, HiChIP,Micro-C, RADICL-seq etc.) and integrating with publicly available datasets
• Engaging with our bioinformatic collaborators to optimize analysis workflows and share expertise
• Supporting experimental biologists by integrating multi-omic analyses to identify optimal targets for functional validation
• Interpreting results of the analysed datasets to create figures for grant proposals (e.g. Horizon EU funds, AIRC etc), for internal as well as external oral presentations, and publications in peer-reviewed journals

ESSENTIAL REQUIREMENTS

• PhD in Bioinformatics/Computational Biology/Computer Science or 5 years hands-on experience in analysis of NGS datasets
• High proficiency level in programming using R and/or Python
• A solid understanding of statistical methodologies commonly applied to biological data analysis
• Proven ability to analyse next-generation sequencing data such as RNA-seq, ChIPseq etc
• Ability to work and think independently, and collaboratively in a highly interdisciplinary environment, with a pro-active attitude
• Good publication record
• Good command of spoken and written English

ADDITIONAL SKILLS

• Experience in analysis of chromatin conformation data such as Hi-C is not mandatory but will be considered a plus
• Familiarity with analysis of long-read Nanopore data will be considered a plus

COMPENSATION PACKAGE

• A yearly gross salary ranging between 45K and 55K, which may include a bonus option depending on your role and contract
• Private health care coverage
• Flexible working time
• Wide range of staff discounts
• Candidates from abroad or Italian citizens who have carried scientific research activity permanently abroad and meet specific requirements, may be entitled to a deduction from taxable income of up to 90% from 6 to 13 years.

This open position is financed by Ministero dell’Università e della Ricerca (MUR) nell’ambito del “Bandro FIS – Fondo Italiano per la Scienza - PROCEDURA COMPETITIVA PER LO SVILUPPO DELLE ATTIVITÀ DI RICERCA FONDAMENTALE, A VALERE SUL FONDO ITALIANO PER LA SCIENZA 2022 – 2023 (BANDO FIS 2)” - MACROSETTORE LS - Life Sciences, D.D. n. 1236 del 01/08/2023, within the “3D-Hubs - Exploring the role of non-coding RNAs in 3D chromatin Hubs” project, Acronym: 3D-Hubs – Grant Agreement number: FIS-2023-02410 – CUP: J53C24004180001

Please submit your application using the online form and including:

• Your CV
• Contact info of 2-3 referees
• A 1 page Cover letter specifying your skills and motivations
• University transcripts
• 3 reference letters

Application’s deadline: March 30th 2025 

To discover more about life at IIT, visit the dedicated section here: https://www.iit.it/en/work-at-iit