진학프로석·박사 채용 접수 플랫폼

Fundação D. Anna de Sommer Champalimaud e Dr. Carlos Montez Champalimaud (Champalimaud Foundation), a private, non-profit research institution, is opening a call for a Postdoc Position. Eligible candidates must hold a PhD or Doctorate degree and will be offered an employment contract with unknown term, within the scope of the research project entitled “Harnessing resident memory T cells in tumor tissue for cancer immunotherapy”; with reference “2023.16121.ICDT” - from the call Nº “SR&TD Projects in all Scientific Domains 2023”, funded by the SELECT APPLICABLE FUNDING ENTITY: Fundação para a Ciência e a Tecnologia (FCT) The contract is to be entered into by and between the Champalimaud Foundation and the selected candidate in accordance with all applicable legislation, including Law-Decree 57/2016, of the 29 the of August of 2016 in its current edition and the General Labour Code, as well as the internal rules and regulations of the Champalimaud Foundation, taking into account the conditions set out in the above mentioned Law-Decree for the recruitment of PhD Holders within the scope of research projects funded by public funds

The selected candidate will:

The position

The Postdoc will work on a project in the research group of Dr Klaas van Gisbergen in the Tissue Immunity Lab at the Champalimaud Foundation. The aim of the project is to understand how T cells differentiate in response to local cues in solid tumors to ultimately employ this knowledge for the development of immunotherapy for improved control of cancer. The postdoc will be working on a research project and tasks will include the planning and design of experiments, supervision of co-workers, writing research manuscripts and presentation of the data at national and international conferences.

The project

In this project we aim to understand the role of tissue-resident memory T cells in immune defense against cancer. Tissue-resident memory T cells are strategically positioned in tissues instead of the circulation to quickly respond to incoming pathogens. A well-defined differentiation program imprints tissue residency in these T cells. Given recent indications that tissue-resident memory T cells are relevant to counter tumor growth, we will explore these T cells in tumor immunity using unique tools, allowing the specific visualization and manipulation of tissue-resident memory T cells. The research will be performed using state-of-the-art techniques in in vivo models, flow cytometry and transcriptional profiling.

The lab

The lab of Tissue Immunity focuses on the development of memory CD8 T cells in infection and tumor settings and the transcriptional and molecular pathways underlying CD8 T cell differentiation. The eventual goal is to improve employment of CD8 T cells for the purpose of cancer immunotherapy. The lab is embedded in the department of Cancer and Physiology at the Champalimaud Foundation that provides a lively, internationally oriented, scientific environment with excellent facilities. The research is strongly multidisciplinary and includes neuroscience, tumor biology and tumor immunology making use of state-of-the-art techniques in in vivo models, molecular biology, flow cytometry and fluorescence microscopy.

Your profile

We are looking for an enthusiastic colleague with a PhD in Biology / Biomedical Sciences, who is highly motivated and has a proven interest in immunology and oncology. The candidate is expected to take initiative and perform well in a team and preferably has hands-on experience with animal experimentation and multi-color flow cytometry and/or transcription profiling and bioinformatics analysis. The ability to publish and present the results of your research is essential.

Employer: Champalimaud Foundation

Department: Champalimaud Research Program | Tissue Immunity Lab

Website: https://fchampalimaud.org/research/groups/van-gisbergen

Number and type of fellowships or contracts to be awarded: 1x contract of 3 years

Application start date: as soon as possible

Application closing date: 2 weeks or 10 business beings

Expected position starting date: Jan 1st 2026

Required Education Level: PhD in Biology, Medicine, Biomedical Sciences or equivalent