Centre de recherche des Cordeliers

Post-doc

Postdoctoral Researcher in Translational Genomics

접수중2026.03.10~2026.05.01

채용 정보

  • 접수 기간

    2026.03.10 00:00~2026.05.01 00:00

  • 접수 방법

    이메일지원더보기

  • 채용 구분

    신입/경력

  • 고용 형태

    계약직

  • 지원 자격

    박사

  • 모집 전공

    생명과학, 생물학, 동물・수의학, 축산학, 작물・원예학, 식품가공학, 농업학, 수산학, 산림・원예학, 농림수산환경생태학, 농림수산바이오시스템공학, 생명공학, 한약학, 약학더보기

  • 기관 유형

    연구기관

  • 근무 지역

    해외(프랑스)더보기

Position title:


Postdoctoral Researcher in Translational Genomics – MOSACLID (ANR 2025) & GENIAL (HORIZON EU) Projects


Contract type:

Fixed-term postdoctoral contract (Inserm)


Duration:

12 months renewable


Starting date:

2026 (1st semester)


Host structure:

Inserm U1138 – Centre de Recherche des Cordeliers (CRC), Paris


Scientific supervisor:

Prof. Jessica Zucman-Rossi


Context and research environment:

The project aims to investigate the role of germline mutant, liver, and hematopoietic somatic mosaicism in the progression of chronic liver diseases to cirrhosis and its complications in HCC, in particular, related to alcohol consumption. The project relies on a unique cohort of 1,750 human liver samples and 400 blood samples and integrates high-resolution genomic approaches (ultra-deep WES, ddPCR, single-cell RNA-seq, spatial transcriptomics).


Main missions:

- Characterization of liver somatic mosaicism.
- Identification of novel genes using ultra-deep WES.
- Analysis of CHIP prevalence and impact in chronic liver diseases.
- Integration of genomic, clinical and histological data in a translational framework.


Main activities:
- Bioinformatic analysis of WES and RNA-seq data.
- Somatic variant detection and annotation.
- Statistical and clinical correlation analyses.
- Preparation of manuscripts and scientific presentations.

근무 예정지

대표Centre de recherche des Cordeliers(해외) : 15 rue de l'École de Médecine

해외(프랑스) : France, Inserm DR Paris 6, Paris, 75006, PARIS, Unité Inserm U1138 - Centre de Recherche des Cordeliers (Sorbonne Université - Inserm - Université Paris Cité) 15 rue de l'Ecole de Medecine 75006 Paris

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관련 키워드

Biological sciencesBiology
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