진학프로석·박사 채용 접수 플랫폼

A post-doctoral position is available in the Motoneuron lab of Dr. Cédric Raoul at the Institute for Neuroscience Montpellier for a collaborative project on leukocyte subsets in ALS pathogenesis.

Amyotrophic lateral sclerosis (ALS) is the third most frequently diagnosed neurodegenerative disease after Alzheimer and Parkinson diseases. ALS is characterized by the loss of motoneurons in the brain and spinal cord. A major mechanism accompanying the symptomatic phase of the disease implicates reactive glial and immune cells that closely surround and influence motoneuron integrity. Development of efficient therapy for ALS faces a significant challenge for identifying mechanisms underlying the selective vulnerability of motoneurons to this cellular environment.

In the present project, we propose to explore the contribution of immune cells to ALS pathogenesis and propose new therapeutic strategies.

About the Institute:

The Institute for Neurosciences of Montpellier (INM) comprises 8 Inserm Teams and a staff of 200 personnel working on sensory-motor deficits and neurodegeneration. Research is devoted to gene discovery and function, developmental biology, neurotransmission and molecular mechanisms of sensory motor disorders and neurodegeneration. INM hosts eleven facilities that provide services and cutting-edge technologies: Animal Facility, Functional Exploration, L2-Stem cells-Organoids, Photonic imaging, Electron microscopy, Clinical Proteomics, Human Neurogenetics, Gene Expression, Protein Engineering, Histology and Methods in Epidemiology.

About the Motoneuron team :

Our mission is to uncover the contribution of non-neuronal cells to motoneuron vulnerability to design innovative therapeutic intervention. We built up a multidisciplinary team with expertise ranging from cellular and molecular physiology of ALS to the genetic and clinic of ALS. We propose to explore the cellular, molecular and electrophysiological aspects of the pathology and link them with clinical expertise and research, to address the intrinsic defects of motoneurons that make them susceptible to signals emerging from other cellular partners.

Appointment to begin last trimester 2025, for a fully-funded period of 1 year, renewable for additional 2 years.

The application should include a cover letter, a CV and in addition three letters of recommendation.