진학프로석·박사 채용 접수 플랫폼

Gdańsk Medical University is seeking a candidate for the position of

Assistant - Assistant Professor (f/m)
with the role of Postdoctoral Researcher
in the Department of Translational Oncology

The selected candidate will participate in the implementation of a research project funded by the National Science Centre (NCN) under the OPUS 29 call, project no. 2025/57/B/NZ3/0184, entitled “Molecular pathways involved in nuclear membrane stress adaptation and its role in breast and prostate cancer”, led by Dr. Paulina Nastały.

LAB DESCRIPTION

In my research, I focus on mechano-oncology, a field that explores how physical and mechanical forces acting on cells influence cancer development and progression. My work aims to better understand how cancer cells respond to stress during disease progression and how these responses contribute to invasion, metastasis, and therapy resistance.

A central aspect of my research is the cell nucleus, which protects genetic information and plays a key role in maintaining cellular integrity. In cancer, structural changes in and around the nucleus can make cells more vulnerable to stress, while also enabling them to adapt and spread more efficiently. I am particularly interested in how cancer cells cope with challenging conditions such as mechanical stress, low oxygen, and other environmental pressures.

By combining concepts from cell biology, biophysics, and cancer research, my work seeks to uncover general principles that govern how cells adapt to stressful environments. Ultimately, my goal is to contribute to a deeper understanding of cancer progression and to support the development of improved diagnostic tools and therapeutic strategies, with a focus on precision and patient-oriented approaches.

https://nastalylab.gumed.edu.pl

THE RESPONSIBILITIES OF THE PERSON EMPLOYED IN THIS POSITION WILL INCLUDE:

• • Conducting experiments in basic molecular biology, including cell culture in 2D and 3D models and their treatment with various factors; performing a wide range of cell-based assays; genetic engineering of cells; qPCR; immunofluorescence and immunohistochemistry; proximity ligation assays; microscopy techniques (widefield, confocal, super-resolution STED, correlative light and electron microscopy, atomic force microscopy, multiplex microscopy, expansion microscopy, time-lapse microscopy); mechanobiology experiments (cell migration under spatial confinement, confinement assays); isolation, preparation, and storage of clinical material; digital pathology; image post-processing and automated quantitative microscopy image analysis; sample preparation for high-throughput drug and siRNA screening; RNA isolation and sequencing; statistical analysis; scientific collaboration with other researchers; interpretation of results and manuscript preparation; participation in international conferences; research visits to collaborating institutions; dissemination of research results; and participation in science communication and outreach activities.
• • Bardziej szczegółowy opis projektu można znaleźć pod adresem https://www.ncn.gov.pl/sites/default/files/listy-rankingowe/2025-03-17-mmatyB0da2/streszczenia/650975-pl.pdf

REQUIREMENTS:

• • Doctoral degree in medicine, biotechnology, molecular biology, cell biology, bioengineering, biophysics, or a related field
• • Experience in basic molecular biology techniques, cell culture, and immunostaining methods
• • Familiarity with at least several advanced microscopy techniques, including confocal microscopy, spinning-disk microscopy, super-resolution microscopy, correlative light and electron microscopy, atomic force microscopy, expansion microscopy, multiplex microscopy, and live-cell imaging
• • Ability to design biologically meaningful experiments to study the organization of the cell nucleus
• • Experience in developing custom, quantitative, and automated microscopy image analysis pipelines will be considered an asset
• • Expertise in mammalian cell engineering, including CRISPR/Cas, lentiviral or transposon-mediated transgenesis, and stable fluorescent/biosensor constructs, is a plus
• • Scientific achievements documented by publications indexed in the JCR list
• • Two letters of recommendation
• • Excellent command of the English language
• • Demonstrated capacity for conceptual thinking and experimental planning
• • Excellent communication skills and motivation to work in an interdisciplinary environment integrating molecular biology, mechanobiology, biophysics, and clinical oncology

WE OFFER:

• An employment contract (the planned project duration is 48 months)
• Stable employment at one of the leading medical universities in Poland
• Work at a medical university that is the only institution in Poland holding research university status
• Additional annual remuneration
• Co-financing of employee holidays (“holiday benefit”)
• Co-financing of children’s holidays
• Subsidies for sports, recreational, and cultural activities
• Employee integration events
• Housing loans
• Subsidies for sports cards
• Opportunity to join group life insurance on preferential terms

FORMAL APPILCATION CRITERIA:

The employee will be employed in accordance with the documentation provided in the OPUS 29 call announcement - LINK

A postdoctoral position is a full-time position planned by the project leader for a person who obtained their doctoral degree in the year of employment in the project or within 12 years prior to 1st January of the year of employment in the project. This period may be extended by documented career breaks. Employment will be carried out in accordance with the additional requirements of the programme.

REQUIRED DOCUMENTS:

• Curriculum vitae (CV) including scientific achievements and a list of publications
• Motivation letter
• Copy of the doctoral diploma (or equivalent)
• Two letters of recommendation (preferably from recent supervisors)

HOW TO APPLY:

• • Interested candidates are invited to submit their applications (CV) via the APPLY button.
• • The application deadline is 28th February 2026.
• • Applications submitted between the application deadline and the end of the job posting publication may still be considered in the recruitment process.
• • Please note that only selected candidates will be contacted.
• • The candidate who receives the highest number of points on the ranking list will be offered the position. The position may be offered to the next candidate on the ranking list if the selected candidate withdraws from signing the employment contract.