진학프로석·박사 채용 접수 플랫폼

Project description
The postdoctoral researcher position is founded by the Czech Science Foundation project ‘Plasmidome structure of the Acinetobacter genus in relation to its ecological diversity‘. This project aims to show the dynamics of Acinetobacter plasmid-mediated gene flow across environmental boundaries.

Plasmids substantially contribute to bacterial evolution, and research on their ecology aids in understanding how opportunistic pathogens like Acinetobacter baumannii adapt to various environmental pressures. However, current research on clinical A. baumannii plasmids remains largely disconnected from studies on environmental Acinetobacter plasmids, and important gene flows between clinical and non-clinical settings may thus remain hidden.

The postdoc will analyze plasmid-mediated gene sharing across Acinetobacter spp. from well-defined environments, each representing varying levels of antibiotic selection pressure (hospitals, farms and pristine nature), using multilayer network analysis. The plasmid sequences will be delivered through whole genome sequencing of available Acinetobacter isolates representing diverse species prevailing in hospitals, farms or pristine nature, as well as ubiquitous species.

Postdoc tasks:

• • Plasmid sequence annotation
• • Building and analyzing multilayer networks based on plasmid sequence sharing across species and environments
• • Interpreting data and writing publications
• • Sequence submission to databases and data management