진학프로석·박사 채용 접수 플랫폼

Université de technologie de Compiègne (Compiègne, France) is recruiting a contractual researcher in the Department of Industrial Process Engineering (GPI) – Integrated Transformations of Renewable Matter laboratory (TIMR UTC – ESCOM) for the YaLiGreen project.

The YaLiGreen project (Multifunctional fabrics based on Yarrowia lipolytica yeast dyes) deals with the production of a green dye by the yeast Yarrowia lipolytica and its application in the textile field (project summary below).

This recruitment is funded by the French National Research Agency (ANR).

Summary

One of the promising alternatives that can partially or completely replace dyes of fossil origin is their microbial production. Despite the multiple advantages compared to plant and animal dyes (e.g., non-competition with food, engineering of targeted molecules, etc.), microbial dyes still face less stability and higher production costs compared to synthetic dyes, which limits their industrial exploitation. In this context, the YaLiGreen project aims to produce a green dye (prodeoxyviolacein) by a modified strain of Yarrowia lipolytica, extract the dye, and use it for fabrics dyeing. The strategies that will be followed in this project consist of 1) boosting the prodeoxyviolacein biosynthesis pathway in the yeast Y. lipolytica, 2) developing a culture medium based on industrial by-products for fermentation, 3) extraction of prodeoxyviolacein using a single-stage process, and 4) its functionalization to obtain color-stable fabrics.

Mission

The successful applicant will be responsible for optimising the fermentation conditions for the yeast Yarrowia lipolytica, optimising the conditions for the accumulation of the dye, its extraction, as well as its purification and analysis. The successful applicant will be responsible in particular for the tasks of WP3 of the project.

Activities

• • Optimize fermentation conditions using Y. lipolytica with industrial by-products and compare production yields to synthetic media;
• • Optimize dye extraction conditions using green solvents;
• • Purify the dyes and develop an analytical technique for quantification;
• • Contribute to data compilation and analysis;
• • Write progress reports and promote the work through communications;
• • Participate in project partner meetings and draft minutes;
• • Present the project results.