Amsterdam UMC
PhD tumor immunology of peritoneal metastasis
접수중2026.01.07~2026.01.18
채용 정보
접수 기간
2026.01.07 00:00~2026.01.18 22:59
접수 방법
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채용 구분
경력 무관
고용 형태
계약직
지원 자격
박사
모집 전공
의약계열더보기
기관 유형
대학교
근무 지역
해외(네덜란드)더보기
연봉 정보
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The treatment of colorectal cancer with peritoneal metastases represents one of the greatest challenges in oncology. Despite intensive research, effective therapies remain scarce and the prognosis for this patient group is poor. Although immunotherapy is promising for various types of cancer, patients with peritoneal metastases generally respond inadequately to these therapies.
Recent research indicates that abnormal tumor glycans play an important role in suppressing anti-tumor immunity. In this KWF-funded project, you will investigate how glycan structures affect immune responses in peritoneal metastasis and whether glycan inhibition can restore anti-tumor immunity.
You will:
- • investigate how tumor-associated glycan structures, particularly sialic acids, influence and suppress immune responses against peritoneal metastases;
- • test in patient material and in vivo models whether sialic acid inhibition reactivates the immune system;
- • analyze and interpret research data using various immunological and cell biological techniques, such as flow cytometry and tumor slice cultures;
- • present research findings at (inter)national conferences and symposia;
- • supervise a bachelor and/or master student during a research internship within the project;
- • contribute to immunology and biochemistry education within the department, for example by teaching work groups or practicals.
Specific Requirements
- • You hold a master's degree in Biomedical sciences or equivalent
- • You have strong analytical and problem-solving skills
- • You have experience with flow cytometry and/or human tissue slice cultures
- • You are willing to work with animal models (an article 9 certificate and prior experience are an advantage)
- • You are a flexible, proactive team player, but can also work independently
- • You have excellent communication skills in English, both written and verbal.
Benefits
- • A flying start to your career in scientific research.
- • Working on translational research in collaboration with motivated researchers from the Netherlands and abroad.
- • You will be employed by Amsterdam UMC Research BV.
- • A contract for 12 months, with the intention to extend for a total of 4 years. The Guideline PhD contract applies to this vacancy.
- • Salary scale OIO: € 3.108 to € 3.939 gross based on full-time employment (depending on education and experience) and a year-end bonus of 8.3%. Calculate your net salary here. Medical doctors are not considered for this position.
- • Holiday hours: 190.4 per year for fulltime and a possibility to save additional hours.
- • Pension accrual with BeFrank, a modern, comprehensible and fairly priced pension.
- • For >7 km each way, 100% reimbursement for public transport travel costs and, for private transport, €0.18 per km up to a maximum of 40 km each way.
- • Do you prefer walking or cycling? Take advantage of our good bike scheme. Moreover, you will receive a reimbursement of €0.18 per km.
근무 예정지
대표해외(네덜란드) : Netherlands, Amsterdam UMC, Amsterdam, 1081HV, De Boelelaan 1117
기관 정보
Amsterdam UMC
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기관유형
대학교(해외)
대표전화
020-566 9111
대표주소
Meibergdreef 9 1105 AZ Amsterdam Zuidoost
홈페이지
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