진학프로석·박사 채용 접수 플랫폼

The postdoctoral researcher will join Sandrine Roulland’s team at the Centre d’Immunologie de Marseille-Luminy (CIML). The group investigates genomic and transcriptomic deregulations involved in the development and progression of human lymphomas.

The successful candidate will contribute to a research program aimed at generating, interpreting, and validating large-scale genomic data to dissect and model the cellular heterogeneity of follicular lymphomas, characterize their oncogenic dependencies, and functionally validate them using CRISPR-based genetic perturbation approaches.

Through integrative analyses, the team also seeks to decipher the biological mechanisms underlying relapse and therapeutic resistance. The researcher will actively contribute to data analysis, synthesis of results, and preparation of scientific publications related to the project.

The postdoc will work in close collaboration with a network of bioinformaticians specializing in the design and development of data analysis pipelines for functional genomics, including CRISPR and single-cell approaches.

Responsibilities

• Generate functional genomics data (CRISPR and single-cell) using human lymphoma patient-derived models.

• Perform and finalize the analysis of CRISPR screening experiments and generate graphical representations of results.

• Validate and consolidate identified targets through CRISPR-based perturbation assays, combined with transcriptomic and proteomic analyses in both human and murine models.

• Evaluate therapeutic combinations using drug screening assays (viability tests, MTS assays, etc.).

• Analyze, interpret, and communicate research findings with collaborators and contribute to scientific publications (manuscript writing, figure preparation).